chromosomal translocation t(2;3)(q35;q21) (renal cell carcinoma)

- chromosomal translocation t(2;3)(q35;q21) involving HSPBAP1 with the putative pseudogene DIRC3 is found in familial renal cell carcinoma 1 - results in hybrid mRNA encoding a truncated HSPBAP1 lacking 1st 36 amino acids - chromosomal translocation t(2;3)(q35;q21) involving DIRC2 is found in familial renal cell carcinoma 1 (RCC1)

Properties

GENERAL: chromosomal translocation FORM: t(2;3)(q35;q21) LOCUS: human chromosome-2 Q35 human chromosome-3 Q21 PATHOLOGY: renal cell carcinoma

References

UniProt :accession Q96EW2, Q96SL1