chromosomal translocation t(2;22)(q33;q12)

- translocation t(2;22)(q33;q12) involving EWSR1 with CREB1 is a cause of angiomatoid fibrous histiocytoma. - translocation generates a EWSR1/CREB1 fusion gene - most common genetic abnormality in angiomatoid fibrous histiocytoma

Properties

GENERAL: chromosomal translocation RELATED: RNA-binding protein EWS cAMP response element-binding protein 1 FORM: t(2;22)(q33;q12) LOCUS: human chromosome-2 Q33 human chromosome-22 Q12 PATHOLOGY: Ewing's sarcoma ABERRANT-GENE:

References

UniProt :accession Q99581