chromosomal translocation t(2;8)(p23;p11.2)

- chromosomal translocation t(2;8)(p23;p11.2 involving ASXL2 with MYST3 is a cause of therapy-related myelodysplastic syndrome - the translocation generates a MYST3-ASXL2 fusion protein

Properties

GENERAL: chromosomal translocation RELATED: myelodysplastic syndrome polycomb group protein ASXL2 histone acetyltransferase MYST3 FORM: t(2;8)(p23;p11.2) LOCUS: human chromosome-2 P23 human chromosome-8 P11.2 PATHOLOGY: myelodysplastic syndrome

References

UniProt :accession Q76L83