chromosomal translocation t(21;22)(q22;q12)

- chromosomal translocation t(21;22)(q22;q12) involving EWSR1 with ERGis a cause of Ewing sarcoma

Properties

GENERAL: chromosomal translocation RELATED: EWS gene erg proto-oncogene FORM: t(21;22)(q22;q12) LOCUS: human chromosome-21 Q22.3 human chromosome-22 Q12 PATHOLOGY: Ewing's sarcoma ABERRANT-GENE: erg proto-oncogene EWS gene

References

Harrison's Principles of Internal Medicine, 14th ed. Fauci et al (eds), McGraw-Hill Inc. NY, 1998, pg 519