chromosomal translocation t(1;14)(q21;q32) (B-ALL)

- chromosomal translocation t(1;14)(q21;q32) involving BCL9 is found in precursor B-cell acute lymphoblastic leukemia (ALL) (one patient); translocation leaves coding region intact, but may have pathogenic effects due to alterations in expression level of BCL9

Properties

GENERAL: chromosomal translocation RELATED: precursor B-lymphoblastic leukemia/lymphoma FORM: t(1;14)(q21;q32) LOCUS: human chromosome-1 Q21 human chromosome-14 Q33.2 PATHOLOGY: precursor B-lymphoblastic leukemia/lymphoma SPLICED-GENES: NIL

References

UniProt :accession O00512