chromosomal translocation t17q23:20q13

Translocation associated with breast cancer, involving genes for BCAS3 & BCAS4.

Properties

GENERAL: chromosomal translocation FORM: t17q23:20q13 LOCUS: human chromosome-17 Q23 CHROMOSOME-23 :ARM q arm (long arm) :SECTION 1 :SUBSECTION 2 PATHOLOGY: acute myeloid leukemia (AML) ABERRANT-GENE: breast carcinoma amplified sequence 4 COMPARTMENT: cytoplasm MOTIF: breakpoint {60-61} breast carcinoma amplified sequence 3 COMPARTMENT: cell nucleus MOTIF: WD repeat {69-114} WD repeat {349-389} WD repeat {403-447} Breakpoint for translocation to form BCAS4-BCAS3 {824-825}

References

UniProt :accession Q8TDM0