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chromosomal translocation t(17;22)(q22;q13)
- chromosomal translocation t(17;22)(q22;q13) involving PDGFB with COL1A1 is found in dermatofibrosarcoma protuberans
Properties
GENERAL: chromosomal translocation
FORM: t(17;22)(q22;q13)
LOCUS: human chromosome-17 Q22
human chromosome-20 Q13
ABERRANT-GENE: platelet-derived growth factor subunit B
CONFIGURATION: dimer
COMPARTMENT: plasma
MOTIF: cysteine-rich region
MOTIF: cysteine residue {*1}
MODIFICATION: cysteine residue {*2}
cysteine residue {*2}
MODIFICATION: cysteine residue {*1}
cysteine residue
MODIFICATION: cysteine residue
signal sequence {1-20}
cysteine residue {C97}
MODIFICATION: cysteine residue {C141}
arginine residue {108}
isoleucine residue {111}
cysteine residue {C124}
MODIFICATION: cysteine residue {C-INTERCHAIN}
cysteine residue {C130}
MODIFICATION: cysteine residue {C178}
cysteine residue {C133}
MODIFICATION: cysteine residue {C-INTERCHAIN}
cysteine residue {C134}
MODIFICATION: cysteine residue {C180}
cysteine residue {C141}
MODIFICATION: cysteine residue {C97}
cysteine residue {C178}
MODIFICATION: cysteine residue {C130}
cysteine residue {C180}
MODIFICATION: cysteine residue {C134}
SECRETED-BY: macrophage
References
UniProt :accession P01127