chromosomal translocation t14q32:t18q21 (follicular lymphoma)

- chromosomal translocation t14q32:t18q24 involving BCL-2 with the immunoglobulin heavy chain gene may be a cause of follicular lymphoma

Properties

GENERAL: chromosomal translocation RELATED: immunoglobulin heavy chain gene bcl-2 proto-oncogene folicular B-cell lymphoma FORM: t14q32:t18q24 LOCUS: human chromosome-14 Q32 human chromosome-18 Q21 PATHOLOGY: folicular B-cell lymphoma ABERRANT-GENE: bcl-2 proto-oncogene immunoglobulin heavy chain gene

References

Cotran et al Robbins Pathologic Basis of Disease, W.B. Saunders Co, Philadelphia, PA 1989 pg 288