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chromosomal translocation t(11;17)(p15;p13)
- chromosomal translocation t(11;17)(p15;p13) involving PHF23 with NUP98 is found in a patient with acute myeloid leukemia
Properties
GENERAL: chromosomal translocation
RELATED: acute myeloid leukemia (AML)
FORM: t(11;17)(p15;p13)
LOCUS: human chromosome-11 P15
human chromosome-17 P13
PATHOLOGY: MALT lymphoma
ABERRANT-GENE: PHD finger protein 23
MOTIF: Breakpoint {120-121}
Ser phosphorylation site {S170}
glutamate-rich region {248-261}
MOTIF: glutamate residue (SEVERAL)
Zn finger PHD-type
NAME: Zn finger PHD-type
SITE: 339-387
EFFECTOR-BOUND: Zn+2
nucleoporin Nup98
COMPARTMENT: cell nucleus
MOTIF: calponin homology domain
NAME: calponin homology domain
SITE: 7-480
glutamate residue {890-894} (5)
References
OMIM :accession 604860