chromosomal translocation t(11;14)(p15;q11) (T-ALL)

- chromosomal translocation t(11,14)(p15;q11) involving LMO1 with TCRD may be a cause of a form of T-cell acute lymphoblastic leukemia (T-ALL)

Properties

GENERAL: chromosomal translocation RELATED: precursor T-lymphoblastic leukemia/lymphoma FORM: t(11;14)(p15;q11) LOCUS: human chromosome-11 P15 human chromosome-14 Q11 ABERRANT-GENE: LMO1 T cell receptor delta (TCRD, TRD) COMPARTMENT: plasma membrane MOTIF: transmembrane domain Tyr phosphorylation site

References

UniProt :accession P25800