chromosomal deletion 17q12 (gastric cancer)

- chromosomal deletion within 17q12 region involving CDK12 producing fusion transcripts with ERBB2 may be a cause of gastric cancer - deletion leads to CDK12-ERBB2 fusion with truncated CDK12 protein not in-frame with ERBB2

Properties

GENERAL: chromosomal deletion RELATED: erbB2 receptor cyclin-dependent kinase 12 FORM: chromosomal deletion 17q12 ABERRANT-GENE:

References

UniProt :accession Q9NYV4