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chromium deficiency
Etiology:
- prolonged parenteral nutrition
Pathology:
- chromium is an essential trace element in humans
- the basis for this need is not fully understood
- no chromium-containing biomolecules with beneficial effects have been characterized
Clinical manifestations:
- severely impaired glucose tolerance
- weight loss
- confusion
- peripheral neuropathy ?
Management:
- chromium is added to normal TPN solutions
Notes:
- chromium supplements (chromium picolinate)
- no benefit in healthy individuals
- might be an improvement in glucose metabolism in diabetics (weak evidence)
Related
chromium [Cr]
General
mineral deficiency
References
- Wikipedia: Chromium deficiency
http://en.wikipedia.org/wiki/Chromium_deficiency