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chromatid-fiber
There are 5 levels of folding of DNA in eukaryotic chromosomes. The chromatid-fiber represents the 5th level of DNA folding. Nucleosomes (1st level of folding) are organized into solenoids (2nd level of folding). The solenoids in turn are folded into loops (3rd level of folding), which in turn form 6 loop rosette structures of 300 Kbp also known radial arrays (4th level of folding). The radial arrays further fold into coils which form chromatid fibers (250 X 700 nm) which form the chromosomal banding seen on chromosomal staining.
Related
chromosomal C-band
chromosomal G-band
chromosomal radial array or rosette
General
DNA motif
macromolecular complex
Properties
SIZE: WIDTH = 250 NM
COMPARTMENT: cell nucleus
References
- Manuelidis L.
A view of interphase chromosomes.
Science. 1990 Dec 14;250(4987):1533-40. Review.
PMID: 2274784
- Filipski J, Leblanc J, Youdale T, Sikorska M, Walker PR.
Periodicity of DNA folding in higher order chromatin structures.
EMBO J. 1990 Apr;9(4):1319-27.
PMID: 2323342
Component-of
non human chromosome
Components
chromosomal G-band