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CHRNA7-FAM7A fusion protein (D-10, CHRNA7-DR1)
Function: (see genetics below)
Structure:
- belongs to the ligand-gated ionic channel (TC 1.A.9) family
Compartment: membrane
Expression: expressed in hippocampus
Genetics:
- encoded by a hybrid gene resulting from duplication of exons 5-10 of CHRNA7 gene fused 3-prime to FAM7A gene (exons A through E),
- the CHRFAM7A gene is in opposite orientation to CHRNA7 gene
- not represented on every human chromosome 15
- not clear whether transcript is actually translated
General
transmembrane 5 protein
Properties
SIZE: MW = 46 kD
entity length = 412 aa
COMPARTMENT: cellular membrane
MOTIF: transmembrane domain {144-164}
transmembrane domain {172-192}
transmembrane domain {205-225}
transmembrane domain {240-254}
transmembrane domain {380-400}
Database Correlations
UniProt Q494W8
PFAM correlations
References
UniProt :accession Q494W8