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Christensenellaceae
Christensenellaceae allegedly associated with a favorable metebolic profile [2]
Epidemiology:
- relative abundance of Christensenellaceae in the human gut is inversely related to host body mass index (BMI) in different populations
- related to a healthy status different disease contexts, including obesity & inflammatory bowel disease
- Christensenellaceae has been associated with human longevity, based on relative abundance of Christensenellaceae is greater in centenarians & supercentenarians in comparison to younger individuals in populations in China [1]
- relative abundance of Christensenellaceae increases with age [1]
Genetics:
- 30-60% in the relative abundance of Christensenellaceae across individuals is due to genetic factors [1]
Specific
Christensenella
General
Firmicutes
Properties
KINGDOM: monera
DIVISION: SCHIZOMYCETES
References
- Waters JL, Ley RE
The human gut bacteria Christensenellaceae are widespread, heritable, and
associated with health.
BMC Biol 2019. Oct 28
PMID: 31660948 PMCID: PMC6819567 Free PMC article. Review.
- Brandhorst S, Levine ME, Wei M et al
Fasting-mimicking diet causes hepatic and blood markers changes indicating reduced
biological age and disease risk.
Nat Commun. 2024 Feb 20;15(1):1309
PMID: 38378685 PMCID: PMC10879164 Free PMC article. Clinical Trial
https://www.nature.com/articles/s41467-024-45260-9