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cheiroarthropathy
Etiology:
- diabetes mellitus, long-standing & poorly controlled
Pathology:
- decreased blood flow to the microvasculature of the hands
- non-enzymatic glycosylation
- non-inflammatory fibrosis of the soft tissue, tendons, & joints of the hands resulting in contractures
Clinical manifestations:
- may present like scleroderma
- thickened skin
- limited mobility of hand & finger joints
Complications:
- related conditions considered part of the cheiroarthropathy spectrum in [2]
- adhesive capsulitis (31%)
- carpal tunnel syndrome (30%)
- flexor tenosynovitis (28%)
- positive prayer sign (22%)
- Dupuytren contracture (9%)
General
joint disease; articular disease; arthropathy
rheumatologic complication of diabetes mellitus
References
- Medical Knowledge Self Assessment Program (MKSAP) 11, American
College of Physicians, Philadelphia 1998
- Larkin ME et al.
Musculoskeletal complications in type 1 diabetes.
Diabetes Care 2014 Jul; 37:1863.
PMID: 24722493
http://care.diabetesjournals.org/content/37/7/1863