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heavy chain constant region-3

Ig constant chain domains & a single extracellular domain of MHC chains are related. These homologous domains are about 100 amino acid residues with a conserved intradomain disulfide. The constant region of immunoglobulins determines the mechanism used to destroy antigen.

General

immunoglobulin constant region; fragment crystallizable region (Fc)

Properties

MOTIF: cysteine residue {CH3.SITE1} MODIFICATION: cysteine residue {CH3.SITE2} cysteine residue {CH3.SITE2} MODIFICATION: cysteine residue {CH3.SITE1}

References

  1. prosite :accession PS00290
  2. Antibody structure http://www.biology.arizona.edu/immunology/tutorials/antibody/structure.html