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Centrosomal protein of 164 kD (protein Cep164, CEP164, KIAA1052)
Function:
- role in microtubule organization &/or maintenance for the formation of primary cilia
Structure: contains 1 WW domain
Compartment:
- centrosome, centriole
- localizes specifically to very distally located appendage structures on the mature centrioles
- persist at centrioles throughout mitosis
Alternative splicing: named isoforms=2
Expression: expressed in several cell lines
General
centrosomal protein
Properties
SIZE: entity length = 1460 aa
MW = 164 kD
MOTIF: WW domain (W/rsp5/WWP domain) {56-89}
lysine-rich region {110-122}
MOTIF: lysine residue (SEVERAL)
glutamate-rich region {468-955}
MOTIF: glutamate residue (SEVERAL)
coiled coil {1154-1206}
Database Correlations
UniProt Q9UPV0
Pfam PF00397
References
UniProt :accession Q9UPV0