CCAAT/enhancer-binding protein-gamma; C/EBP gamma (CEBPG)

Function: - transcription factor & DNA-binding protein - binds to positive regulatory element-1 (PRE-1) of the IL-4 gene - might change the DNA-binding specificity of other transcription factors & recruit them to unusual DNA sites - binds DNA as a dimer & can form stable heterodimers with C/EBP alpha & C/EBP beta & with Fos protein Structure: - belongs to the bZIP family, C/EBP subfamily - contains 1 bZIP domain Compartment: nucleus

Properties

CONFIGURATION: dimer SIZE: entity length = 150 aa MW = 16 kD COMPARTMENT: cell nucleus MOTIF: DNA-binding motif SITE: 68-86 leucine zipper SITE: 97-118 FOR-BINDING-VIA: leucine zipper

Database Correlations

OMIM 138972 UniProt P53567 Pfam PF07716 Kegg hsa:1054

References

UniProt :accession P53567