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corneodesmosin (S protein, CDSN)

Compartment: - secreted - found in corneodesmosomes Expression: exclusively expressed in skin Polymorphism: - genetic variation in CDSN may be associated with susceptibility to psoriasis Pathology: - defects in CDSN are a cause of hypotrichosis simplex of scalp

General

glycoprotein

Properties

SIZE: MW = 51 kD entity length = 529 aa MOTIF: signal sequence {1-32} serine-rich region {62-464} MOTIF: serine residue (SEVERAL) N-glycosylation site {N172}

Database Correlations

OMIM correlations UniProt Q15517

References

UniProt :accession Q15517