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CD55 + CD59 erythrocytes in blood
Indications:
- evaluation of paroxysmal nocturnal hemoglobinuria
Clinical significance:
- hemolysis in paroxysmal nocturnal hemoglobinuria is caused by the absence of decay-accelerating factor (CD55) & the membrane inhibitor of membrane lysis (CD59)
Related
CD55; complement decay accelerating factor (DAF)
CD59; CD59 glycoprotein; membrane attack complex inhibition factor; MACIF; MAC-inhibitory protein; MAC-IP; protectin; MEM43 antigen; membrane inhibitor of reactive lysis; MIRL; 20 kD homologous restriction factor; HRF-20; HRF20; 1F5 antigen (MIC11, MIN1, MIN2, MIN3, MSK21)
Specific
CD55 + CD59 erythroctyes in blood %
General
CD55 + CD59 cells in blood
References
- Medical Knowledge Self Assessment Program (MKSAP) 17,18.
American College of Physicians, Philadelphia. 2015, 2018