Search
CD52; CAMPATH-1 antigen; Cambridge pathology 1 antigen; epididymal secretory protein E5; CDw52 (CDW52, HE5)
Function:
- may play a role in carrying & orienting carbohydrate, as well as having a more specific role
Compartment: cell membrane; lipid-anchor, GPI-anchor
Expression:
- thymocytes
- lymphocytes
- monocytes/macrophages
- eosinophils
- epithelial cells lining male reproductive tract
Pathology:
- expressed in most lymphoid malignancies
Pharmacology:
- target of antitumor monoclonal antibody alemtuzumab (Campath-1H).
Related
CD52 Ag in tissue
General
cluster-of-differentiation antigen; cluster designation antigen; CD antigen
glypiated protein
Properties
SIZE: entity length = 61 aa
MW = 7 kD
COMPARTMENT: plasma membrane
CELL-REGION: apical region
CELL: epithelial cell
MOTIF: signal sequence {1-24}
N-glycosylation site {N27}
glycosyl phosphatidylinositol [GPI] membrane anchor {N36}
N-glycosylation site {N40}
Database Correlations
OMIM 114280
UniProt P31358
Entrez Gene 1043
Kegg hsa:1043
References
- UniProt :accession P31358
- http://www.pathologyoutlines.com/cdmarkers.html
15 October 2002
- Entrez Gene :accession 1043