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CD320; 8D6 antigen; FDC-signaling molecule 8D6; FDC-SM-8D6; 8D6A (UNQ198/PRO224)
Function:
- CD320 augments the proliferation of plasma cell precursors induced by IL-10
Structure: contains 2 LDL-receptor class A domains
Compartment: membrane
Expression: expressed abundantly on follicular dendritic cells
General
cluster-of-differentiation antigen; cluster designation antigen; CD antigen
Properties
SIZE: MW = 29 kD
entity length = 282 aa
COMPARTMENT: plasma membrane
MOTIF: signal sequence {1-30}
LDL-receptor class A {53-90}
MOTIF: cysteine residue {C54}
MODIFICATION: cysteine residue {C67}
cysteine residue {C61}
MODIFICATION: cysteine residue {C80}
cysteine residue {C67}
MODIFICATION: cysteine residue {C54}
cysteine residue {C74}
MODIFICATION: cysteine residue {C89}
cysteine residue {C80}
MODIFICATION: cysteine residue {C61}
cysteine residue {C89}
MODIFICATION: cysteine residue {C74}
proline-rich region
SITE: 101-104
MOTIF: proline residue (SEVERAL)
N-glycosylation site {N126}
LDL-receptor class A {131-168}
MOTIF: cysteine residue {C132}
MODIFICATION: cysteine residue {C145}
cysteine residue {C139}
MODIFICATION: cysteine residue {C158}
cysteine residue {C145}
MODIFICATION: cysteine residue {C132}
cysteine residue {C152}
MODIFICATION: cysteine residue {C167}
cysteine residue {C158}
MODIFICATION: cysteine residue {C139}
cysteine residue {C167}
MODIFICATION: cysteine residue {C152}
N-glycosylation site {N195}
N-glycosylation site {N213}
transmembrane domain {230-250}
MOTIF: alanine-rich region {233-236}
MOTIF: alanine residue (SEVERAL)
Database Correlations
OMIM 606475
UniProt Q9NPF0
Pfam PF00057
References
UniProt :accession Q9NPF0