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CD153; tumor necrosis factor ligand superfamily member 8; CD30 ligand; CD30-L (TNFSF8, CD30L, CD30LG)

Function: - cytokine that binds to TNFRSF8/CD30 - induces proliferation of T-cells Structure: - homotrimer (probable) - belongs to the tumor necrosis factor family Compartment: - membrane; single-pass type 2 membrane protein

General

cluster-of-differentiation antigen; cluster designation antigen; CD antigen glycoprotein human longevity protein tumor necrosis factor (TNF) family protein

Properties

SIZE: entity length = 234 aa MW = 26 kD COMPARTMENT: cellular membrane MOTIF: transmembrane domain {38-62} N-glycosylation site {N81} N-glycosylation site {N109} cysteine residue {C151} MODIFICATION: cysteine residue {C177} N-glycosylation site {N153} cysteine residue {C177} MODIFICATION: cysteine residue {C151} N-glycosylation site {N189} N-glycosylation site {N201}

Database Correlations

OMIM 603875 UniProt P32971 Pfam PF00229 Entrez Gene 944 Kegg hsa:944

References

  1. UniProt :accession P32971
  2. Entrez Gene :accession 944