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CCND1 gene rearrangement

Indications: - evaluation of mantle cell lymphoma Clinical significance: - chromosomal translocation t(11:14) involving CCND1* is diagnostic for mantle cell lymphoma [1] * CCND1 (PRAD1) is the gene for cyclin D1

Related

cyclin D1 (parathyroid adenomatosis-1 [PRAD1] protein or bcl-1 proto-oncogene protein, CCND1, BCL1) parathyroid adenomatosis [PRAD]-1 gene, CCND1 or bcl-1

General

chromosome rearrangement testing

References

  1. Medical Knowledge Self Assessment Program (MKSAP) 17, American College of Physicians, Philadelphia 2015