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chromobox protein homolog 2 (CBX2)
Function:
- component of polycomb group (PcG) multiprotein PRC1 complex
Structure:
- contains 1 A.T hook DNA-binding domain
- contains 1 chromo domain
Compartment: nucleus
Alternative splicing: named isoforms=2
General
chromobox protein homolog
Properties
SIZE: entity length = 532 aa
MW = 56 kD
COMPARTMENT: cell nucleus
MOTIF: chromodomain
NAME: chromodomain
SITE: 12-70
FOR-BINDING-OF: heterochromatin
A+T hook
SITE: 75-87
serine-rich region {87-120}
MOTIF: serine residue (SEVERAL)
nuclear translocation signal {163-168}
serine-rich region {464-469}
MOTIF: serine residue (SEVERAL)
Database Correlations
OMIM 602770
MORBIDMAP 602770
UniProt Q14781
Pfam PF00385
Entrez Gene 84733
Kegg hsa:84733
References
UniProt :accession Q14781
Component-of
Polycomb group multiprotein PRC1 complex (PcG PRC1 complex, hPRC-H, PcG repressive complex 1)