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catenin
Function:
- association of catenins to cadherins produces a complex which is linked to the actin filament network, & which seems to be of primary importance for cadherins cell-adhesion properties
- catenin-binding sites in intracellular domain of cadherins are essential for cell-cell adhesion & adhesion of contact sites to cytoskeleton
Related
cadherin
Specific
alpha catenin
beta catenin
catenin delta-1; p120 catenin; p120(ctn); cadherin-associated Src substrate; CAS; p120(cas) (CTNND1, KIAA0384)
catenin delta-2; delta-catenin; neural plakophilin-related ARM-repeat protein; NPRAP; neurojungin; GT24 (CTNND2, NPRAP)
catenin gamma; junction plakoglobin; desmoplakin-3 (JUP, CTNNG, DP3)
General
adhesion receptor
Properties
COMPARTMENT: cytoplasm
MOTIF: focal adhesion site
transmembrane domain
References
- Takeichi M.
Cadherin cell adhesion receptors as a morphogenetic regulator.
Science. 1991 Mar 22;251(5000):1451-5. Review.
PMID: 2006419