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casein kinase

Classification: - numerical designations for casein kinase 1 & casein kinase 2 derive from the elution pattern from DEAE-cellulose chromatography Function: - casein kinases preferentially phosphorylate acidic proteins such as caseins Notes: - the name casein kinase derives from the fact that casein is a convenient protein substrate that is generally used to assay activity

Interactions

molecular events

Specific

casein kinase 1 casein kinase 2 mammary gland casein kinase

General

serine/threonine kinase

Properties

STATE: active state MOTIF: S/T phosphorylation site kinase domain MOTIF: ATP-binding site NAME: ATP-binding site

References

  1. Allende JE, Allende CC. Protein kinases. 4. Protein kinase CK2: an enzyme with multiple substrates and a puzzling regulation. FASEB J. 1995 Mar;9(5):313-23. Review. PMID: 78960005
  2. UniProt :accession Q8N752