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cardiac right to left shunt
See congenital heart disease
Etiology:
1) patent foramen ovale (38%)
2) pulmonary arteriovenous malformation (28%)
3) 5% with both
4) Eisenmenger's syndrome
5) No association of shunting with migraine
Epidemiology:
- 71% of healthy volunteers have some right-to-left shunting
- shunt size mostly 'small to moderate'
Laboratory:
- complete blood count: erythrocytosis
- pulse oximetry or arterial blood gas: hypoxia
Special laboratory:
- echocardiogram:
- identified by saline contrast echocardiogram (bubble study)
Management:
- consider air filters on intravenous lines in hospitalized patients to prevent paradoxical air embolism [2]
General
cardiac shunt
References
- Woods TD et al.
Small- and moderate-size right-to-left shunts identified
by saline contrast echocardiography are normal and unrelated
to migraine headache.
Chest 2010 Aug; 138:264.
PMID: 20154080
- Medical Knowledge Self Assessment Program (MKSAP) 16, 17
American College of Physicians, Philadelphia 2012, 2015