Ca+2 channel

Function: - ion channel through which Ca⁺² current flows - Ca⁺² channels allow Ca⁺² to flow into the cytoplasm from the extracellular space or intracellular compartment along the Ca⁺² concentration gradient

Specific

cGMP-gated channel inositol triphosphate [IP3] receptor P400 (ITPR, IP3-R) kainate receptor polycystin-2; polycystic kidney disease 2 protein; autosomal dominant polycystic kidney disease type II protein; polycystwin; R48321 (PKD2) ryanodine receptor (RyR) short transient receptor potential channel 4 (TrpC4, Trp-related protein 4, hTrp-4, hTrp4, TRPC4) short transient receptor potential channel 5 (TrpC5, Htrp-5, Htrp5, TRP5) short transient receptor potential channel 7 (TrpC7, TRP7 protein, TRP7) transient receptor potential cation channel subfamily M member 1 (long transient receptor potential channel 1, LTrpC1, melastatin-1, TRPM1, LTRPC1, MLSN, MLSN1) transient receptor potential cation channel subfamily M member 2 (TrpM2, long transient receptor potential channel 2, LTrpC2, LTrpC-2, transient receptor potential channel 7, TrpC7, estrogen-responsive element-associated gene 1 protein, EREG1, KNP3) transient receptor potential cation channel subfamily M member 3 (TrpM3, long transient receptor potential channel 3, LTrpC3, melastatin-2, MLSN2, KIAA1616) transient receptor potential cation channel subfamily M member 8 (TrpM8, transient receptor potential-p8, Trp-p8, long transient receptor potential channel 6, LTrpC6, TRPP8) transient receptor potential cation channel subfamily V (TRPV) transient receptor potential cation channel subfamily V member 1; osm-9-like TRP channel 1; vanilloid receptor 1; VR1 capsaicin receptor (TRPV1, OTRPC1) transient receptor potential cation channel subfamily V member 2 (TrpV2, osm-9-like TRP channel 2, OTRPC2, vanilloid receptor-like protein 1, VRL-1, VRL) transient receptor potential cation channel subfamily V member 3 (TrpV3, vanilloid receptor-like 3, VRL-3) transient receptor potential cation channel subfamily V member 4 (TrpV4, vanilloid receptor-like 2, VRL-2, osm-9-like TRP channel 4, OTRPC4, vanilloid receptor-related osmotically-activated channel, VR-OAC, transient receptor potential protein 12, TRP12, VRL2, VROAC) voltage-dependent Ca+2 channel

Properties

COMPARTMENT: cellular membrane MOTIF: membrane region ION-PERMEABILITY: Ca+2