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calcipotriene; calcipotriol (Dovonex, Dovobet)

Tradename: Dovonex. A synthetic 1,25 dihydroxy vitamin D3 analog. Indications: 1) psoriasis 2) venous stasis ulcers (insufficiency) Dosage: topical: apply BID Ointment 0.005%. 60g & 100g. Monitor: - serum Ca+2 baseline & regularly - discontinue if hypercalcemmia & monitor serum Ca+2 weekly until levels normalize [4] Adverse effects: 1) not common (1-10%) - burning, stinging, pruritus, erythema, facial dermatitis 2) transient elevation of serum Ca+2 may occur

Interactions

drug interactions

General

vitamin D

Properties

MISC-INFO: pregnancy-category C safety in lactation ?

Database Correlations

PUBCHEM correlations

References

  1. The Pharmacological Basis of Therapeutics, 9th ed. Gilman et al, eds. Permagon Press/McGraw Hill, 1996
  2. Kaiser Permanente Northern California Regional Drug Formulary, 1998
  3. Drug Information & Medication Formulary, Veterans Affairs, Central California Health Care System, 1st ed., Ravnan et al eds, 1998
  4. Prescriber's Letter 17(7): 2010 Recommended Lab Monitoring for Common Medications Detail-Document#: 260704 (subscription needed) http://www.prescribersletter.com

Component-of

beclomethasone/calcipotriene (Taclonex) betamethasone/calcipotriene (Enstilar)