cadherin EGF LAG seven-pass G-type receptor 2 (epidermal growth factor-like 2, multiple epidermal growth factor-like domains 3, Flamingo 1, CELSR2, CDHF10, EGFL2, KIAA027, MEGF3)

Function: - receptor with role in cell/cell signaling during nervous system formation (putative) Compartment: membrane Expression: highest expression in brain & testis

Properties

SIZE: MW = 317 kD entity length = 2923 aa COMPARTMENT: cellular membrane MOTIF: exoplasmic domain {1-2380} MOTIF: signal sequence {1-31} cadherin domain {182-1146} (9) N-glycosylation site {N1036} N-glycosylation site {N1076} N-glycosylation site {N1182} N-glycosylation site {N1212} EGF domain {1228-1366} (3) LAMININ G-LIKE 1 {1367-1571} EGF domain {1574-1610} LAMININ G-LIKE 2 {1614-1791} EGF domain {1793-1828} N-glycosylation site {N1827} EGF domain {1829-1971} (4) N-glycosylation site {N2024} N-glycosylation site {N2043} N-glycosylation site {N2061} GPS {2316-2368} N-glycosylation site {N2323} N-glycosylation site {N2345} transmembrane domain {2381-2401} cytoplasmic loop {2402-2416} transmembrane domain {2417-2437} exoplasmic loop {2438-2438} transmembrane domain {2439-2459} cytoplasmic loop {2460-2480} transmembrane domain {2481-2501} exoplasmic loop {2502-2519} transmembrane domain {2520-2540} cytoplasmic loop {2541-2560} transmembrane domain {2561-2581} exoplasmic loop {2582-2591} transmembrane domain {2592-2612} cytoplasmic domain {2613-2923} MOTIF: glutamate-rich region {2743-2752} MOTIF: glutamate residue (SEVERAL)

Database Correlations

OMIM 604265 UniProt Q9HCU4 PFAM correlations

References

UniProt :accession Q9HCU4