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Zn finger C3H1-type
Function:
- interacts with the 3'-untranslated region of mRNAs
Structure:
- conserved cysteine-histidine arrangement, C-x(8)-C-x(5)-C-x(3)-H
Expression:
- present in many eukaryotic proteins from yeast to mammals
- very often present in two copies
- proteins known to contain a C3H1-type zinc finger include:
a) mammalian tristetraprolin proteins
b) eukaryotic TIS/CTH family
c) Cpsf4
d) makorin-1, makorin-3 (ZNF127)
Related
DNA motif
General
Zinc finger (cysteine finger)
Properties
EFFECTOR-BOUND: Zn+2
References
Prosite :accession PS50103