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echinocyte (burr cell)
Echinocytes (burr cells) are uniformly spiculated erythrocytes (multiple spiny cytoplasmic projections)
Etiology:
- seen in association with uremia & loss of red cell volume.
Differential diagnosis:
- distinguished from acanthocytes which have irregularly distributed spicules
* acanthocytes may be seen in severe or chronic liver disease, hence also uremia?
Laboratory:
- burr cells in blood
- burr cells in CSF
- burr cells in urine sediment
Properties
GENERAL: erythrocyte-variant
QUANTITY: 4.2E12-6.2E12 CELLS/UL