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burning mouth syndrome

Etiology: - disorder associations - food allergy - drug allergy - diabetes mellitus - menopause - generalized anxiety disorder - depression - lichen planus - denture use - dental treatment - postulated causes - vitamin B12 deficiency - iron deficiency Epidemiology: - prevalence: 0.7% (USA); up to 7% in Europe - more prevalent in older adults & women - female:male ratio = 7:1 Pathology: - salivary function is normal Clinical manifestations: - burning sensation or other dysesthesia of the oral mucosa - generally involves anterior 2/3 of tongue, hard palate & lips - gingival tissue less frequently involved - symptoms rarely involve the soft palate or mouth floor - dysgeusia common - xerostomia common Laboratory: - serum vitamin B12 - iron studies - serum iron, TIBC, serum ferritin - fungal culture of oral cavity for oropharyngeal candidiasis Management: - no treatment guidelines - treatments that have been used include - topical rinse - lidocaine, capsaicin, doxepin - oral agents - antidepressants - opiates - anticonvulsants - benzodiasepines

General

syndrome stomatognathic (mouth) disease

References

  1. Geriatric Review Syllabus, 7th edition Parada JT et al (eds) American Geriatrics Society, 2010 - Geriatric Review Syllabus, 9th edition (GRS9) Medinal-Walpole A, Pacala JT, Porter JF (eds) American Geriatrics Society, 2016 - Geriatric Review Syllabus, 10th edition (GRS10) Harper GM, Lyons WL, Potter JF (eds) American Geriatrics Society, 2019 - Geriatric Review Syllabus, 11th edition (GRS11) Harper GM, Lyons WL, Potter JF (eds) American Geriatrics Society, 2022
  2. Gurvits GE, Tan A. Burning mouth syndrome. World J Gastroenterol. 2013 Feb 7;19(5):665-72. Review. PMID: 23429751 Free PMC Article
  3. Jaaskelainen SK Pathophysiology of primary burning mouth syndrome. Clin Neurophysiol. 2012 Jan;123(1):71-7. Review. PMID: 22030140
  4. Patton LL, Siegel MA, Benoliel R, De Laat A. Management of burning mouth syndrome: systematic review and management recommendations. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 Mar;103 Review. PMID: 17379153