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WD repeat-containing protein 11; bromodomain & WD repeat-containing protein 2; WD repeat-containing protein 15 (WDR11, BRWD2, KIAA1351, WDR15)
Structure: contains 9 WD repeats
Compartment: membrane (potential)
Expression: ubiquitous
Pathology:
- chromosomal translocation t(10;19)(q26;q13.3) involving WDR11 with ZNF320 is found in a form of glioblastoma
General
membrane protein
phosphoprotein
WD repeat protein family
Properties
SIZE: entity length = 1224 aa
MW = 137 kD
COMPARTMENT: cellular membrane
MOTIF: WD repeat {59-108}
WD repeat {111-154}
WD repeat {354-393}
Ser phosphorylation site {S402}
Ser phosphorylation site {S406}
WD repeat {471-510}
WD repeat {566-605}
WD repeat {708-745}
WD repeat {747-787}
WD repeat {793-831}
WD repeat {893-940}
Tyr phosphorylation site {Y1086}
transmembrane domain {1127-1147}
Database Correlations
OMIM 606417
UniProt Q9BZH6
Pfam PF00400
Entrez Gene 55717
Kegg hsa:55717
References
UniProt :accession Q9BZH6