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brown nails; longitudinal brown lines; black nails
Abnormal pigment affecting the nail plate or nail bed or both.
Etiology:
1) pigmentation of the nail plate
- Addison's disease
- hemochromatosis
- gold therapy
- arsenic intoxication
- azidothymidine [2]
- minocycline [2]
- Nelson's syndrome
2) pigmentation of the nail plate & bed
- melanoma (may also pigment proximal nail fold)
- suspect melanoma when proximal nail fold involved
3) pigmentation of the nail bed
- melanocytic nevus of nail matrix
- solar lentigo
- subungual hematoma
- brown linear bands are a common finding in black or brown-skinned individuals (melanonychia)
Pathology:
- increased melanin production by nail matrix melanocytes [3]
Clinical manifestations:
- longitudinal brown lines may extend from tip of nail into the lunula [3]
- these are benign if < 3 mm in width
Image [3]
Special laboratory:
- nail biopsy if suspicious for melanoma
- > 3 mm in width
- irregular or blurred borders to the band
- brown black discoloration of the proximal nail fold (skin proximal to nail)
Management:
- reassurance & observation in the absence of suspicion of melanoma
Related
Hutchinson's sign; periungual pigmentation
Specific
melanonychia; longitudinal melanonychia; melanonychia striata
General
nail disease
References
- Color Atlas & Synopsis of Clinical Dermatology, Common
& Serious Diseases, 3rd ed, Fitzpatrick et al, McGraw Hill, NY,
1997, pg 503
- Medical Knowledge Self Assessment Program (MKSAP) 17,
American College of Physicians, Philadelphia 2015
- Brady MP
Fingernail and Toenail Abnormalities: Nail the Diagnosis.
Medscape March 17, 2021
https://reference.medscape.com/slideshow/fingernail-abnormalities-6002456