BRISC complex

Function: - specifically cleaves Lys-63-linked ubiquitin in various substrates - Lys-63-specific deubiquitination associated with the COP9 signalosome complex occurs via the interaction of the BRISC complex with the COP9 signalosome complex - BRCC3 is the catalytic subunit Structure: - subunits: - FAM175B/ABRO1, BRCC3/BRCC36, BRE/BRCC45 & MERIT40/NBA1

Properties

SUBUNITS: NIL

References

UniProt :accession P46736