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BRCA1 C-terminal (BRCT) motif

Seen in many proteins with role in genome integrity control; appear to participate in specific interactions with target proteins. In BRCA1, mediates double strand break repair/ homologous recombination.

General

binding site domain

References

  1. Cantor et al. Cell 105:149-60 2001
  2. prosite :accession PS50172