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BRCA2 gene mutation

see BRCA1/BRCA2 genotyping Complications: - cumulative risk for breast cancer by age 80 - 72% in BRCA1 carriers & 69% in BRCA2 carriers - cumulative risk for ovarian cancer by age 80 - 44% in BRCA1 carriers & 17% in BRCA2 carriers [1]

Related

BRCA1/BRCA2 genotyping BRCA2 gene mutation positive breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein, BRCA2, FACD, FANCD1)

General

BRCA gene mutation (BRACAnalysis CDx)

References

  1. Kuchenbaecker KB, Hopper JL, Barnes DR et al. Risks of breast, ovarian, and contralateral breast cancer for BRCA1 and BRCA2 mutation carriers. JAMA 2017 Jun 20; 317:2402. PMID: 28632866 http://jamanetwork.com/journals/jama/article-abstract/2632503