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BOOST study (stem cell infusion for MI)
Study characteristics: 60 patients
Autologous bone marrow stem cells infused into revascularized coronary arteries after myocardial infarction, 5 days after revascularization.
Group receiving stem cells had 6% higher LVEF than controls after 6 months.
No difference in rates of ventricular ectopy or restenosis.
General
clinical trial
References
Journal Watch 24(16):126, 2004
Wollert KC, Meyer GP, Lotz J, Ringes-Lichtenberg S, Lippolt P,
Breidenbach C, Fichtner S, Korte T, Hornig B, Messinger D,
Arseniev L, Hertenstein B, Ganser A, Drexler H.
Intracoronary autologous bone-marrow cell transfer after myocardial
infarction: the BOOST randomised controlled clinical trial.
Lancet. 2004 Jul 10;364(9429):141-8.
PMID: 15246726