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radioisotope bone scan; bone scintigraphy; osseous survey
Indications:
1) bone neoplasm
2) bone metastases
3) hypertrophic osteoarthropathy
- hypertrophic pulmonary osteoarthropathy
4) osteomyelitis
5) nondisplaced bone fractures
6) reflex sympathetic dystrophy
7) Paget's disease of the bone
Contraindications:
- not useful for multiple myeloma (lesions often purely lytic) [1]
Clinical significance:
- patterns of uptake
- increased uptake in skull, femur & pelvis in Paget's disease of the bone
Mechanism of action:
- detects osteoblastic activity [1]
Specific
radioisotope bone scan for metastases
General
scintigraphy (radionuclide test)
References
- Medical Knowledge Self Assessment Program (MKSAP) 11, 16, 18.
American College of Physicians, Philadelphia 1998, 2012, 2018.
- Wikipedia: Bone scintigraphy
http://en.wikipedia.org/wiki/Bone_scintigraphy