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bone morphogenetic protein 6; BMP-6; VG-1-related protein; VG-1-R; VGR-1 (BMP6, VGR)
Function:
- induces cartilage & bone formation
- interacts with SOSTDC1 (putative)
Structure: belongs to the TGF-beta family
Compartment: secreted (putative)
General
bone morphogenetic protein (BMP)
TGF-beta family protein
Properties
SIZE: entity length = 513 aa
MW = 57 kD
COMPARTMENT: extracellular compartment
MOTIF: signal sequence {1-20}
N-glycosylation site {N241}
N-glycosylation site {N269}
N-glycosylation site {N386}
N-glycosylation site {N404}
cysteine residue {C412}
MODIFICATION: cysteine residue {C478}
cysteine residue {C441}
MODIFICATION: cysteine residue {C510}
cysteine residue {C445}
MODIFICATION: cysteine residue {C512}
N-glycosylation site {N454}
cysteine residue {C477}
MODIFICATION: cysteine residue {C-INTERCHAIN}
cysteine residue {C478}
MODIFICATION: cysteine residue {C412}
cysteine residue {C510}
MODIFICATION: cysteine residue {C441}
cysteine residue {C512}
MODIFICATION: cysteine residue {C445}
Database Correlations
OMIM 112266
UniProt P22004
PFAM correlations
Entrez Gene 654
Kegg hsa:654
References
- UniProt :accession P22004
- Wikipedia; Note: bone morphogenetic protein 6 entry
http://en.wikipedia.org/wiki/bone_morphogenetic_protein_6