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bone morphogenetic protein 5; BMP-5 (BMP5)
Function:
- induces cartilage & bone formation
Structure:
- homodimer; disulfide-linked (putative)
- belongs to the TGF-beta family
Compartment: secreted
Expression: expressed in the lung & liver
General
bone morphogenetic protein (BMP)
TGF-beta family protein
Properties
SIZE: entity length = 454 aa
MW = 52 kD
COMPARTMENT: extracellular compartment
MOTIF: signal sequence {1-30}
N-glycosylation site {N211}
N-glycosylation site {N327}
N-glycosylation site {N345}
cysteine residue {C353}
MODIFICATION: cysteine residue {C419}
cysteine residue {C382}
MODIFICATION: cysteine residue {C451}
cysteine residue {C386}
MODIFICATION: cysteine residue {C453}
N-glycosylation site {N395}
cysteine residue {C418}
MODIFICATION: cysteine residue {C-INTERCHAIN}
cysteine residue {C419}
MODIFICATION: cysteine residue {C353}
cysteine residue {C451}
MODIFICATION: cysteine residue {C382}
cysteine residue {C453}
MODIFICATION: cysteine residue {C386}
Database Correlations
OMIM 112265
UniProt P22003
PFAM correlations
Entrez Gene 653
Kegg hsa:653
References
- UniProt :accession P22003
- Wikipedia; Note: bone morphogenetic protein 5 entry
http://en.wikipedia.org/wiki/bone_morphogenetic_protein_5