Contents

Search

blueberry

Components: - ellagitannins, proanthocyanidins, anthocyanins, & other flavonoids - pterostilbene Pharmacokinetics: - ellagitannins, proanthocyanidins, anthocyanins, & other flavonoids in berrys are poorly absorbed & highly metabolized - parent compounds, metabolites & conjugates detectable in human tissue Clinical manifestationw: - discoloration of teeth & tongue - blueberry consumption can improve endothelial function in healthy persons & at-risk populations [6] - flavonoids including anthocyanins in blueberries may mitigate macular degeneration [6] Clinical trials: - 12% improvement in memory over 2 year period in subjects age 50-84 consuming 1 cup of frozen blueberries/day; No study controls [2] - lowers serum triglycerides (40%) & LDL cholesterol (20%) [3]

General

berry

References

  1. Seeram NP Dietary polyphenols from berry fruits: metabolism and health Aging: Mechanisms and Prevention 34th Annual Meeting of the American Aging Association June 3-6, 2005, Oakland CA
  2. Raphaelson HA, Martin RJ et al Memory-score improvement observed during two-year blueberry study. Aging: Mechanisms and Prevention 34th Annual Meeting of the American Aging Association June 3-6, 2005, Oakland CA BlueberryStudy.com/measurements
  3. Rimando A, USDA Proceedings of the 38th Annual Meeting of the American Aging Association: Integrative Biology: Hormones, Signaling, and Aging. May 29-June 1, 2009, Scottsdale, AZ
  4. McNamara D Blue' in Blueberries Tied to BP Lowering that Rivals Medication. Medscape - Mar 01, 2019. https://www.medscape.com/viewarticle/909717 - Rodriguez-Mateos A et al Circulating anthocyanin metabolites mediate vascular benefits of blueberries: insights from randomized controlled trials, metabolomics, and nutrigenomics. J Gerontol A Biol Sci Med Sci. 2019 Jun 18;74(7):967-976 PMID: 30772905 https://academic.oup.com/biomedgerontology/advance-article-abstract/doi/10.1093/gerona/glz047/5321875
  5. Bosch-Morell F, Villagrasa V, Ortega T et al Medicinal plants and natural products as neuroprotective agents in age-related macular degeneration. Neural Regen Res. 2020 Dec;15(12):2207-2216. PMID: 32594032 PMCID: PMC7749482 Free PMC article. Review.
  6. Woolf EK, Lee SY, Ghanem N, Vazquez AR, Johnson SA. Protective effects of blueberries on vascular function: A narrative review of preclinical and clinical evidence. Nutr Res. 2023 Dec;120:20-57. PMID: 37913730 Review.