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biliary cast syndrome

Etiology: - liver transplantation for primary biliary cirrhosis Pathology: - dilatation of the lower end of the common bile duct - filling defect at the upper end of the common bile duct Laboratory: - bilirubin in serum -> marked hyperbilirubinemia - mildly elevated serum ALT, serum AST (< 100 U/L) Radiology: - magnetic resonance cholangiopancreatography: thinning of intrahepatic bile duct Management: - surgery & a 2nd liver tranplantion may be necessary

General

biliary disease

References

  1. Wang K, Wu S Biliary Cast Syndrome. N Engl J Med 2020; 382:e13. Fet 27. PMID: 32101668 https://www.nejm.org/doi/full/10.1056/NEJMicm1909877