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beta lactamase
An enzyme produced by bacteria that hydrolyzes beta-lactam ring of beta-lactam antibiotics.
Specific
beta lactamase A
beta lactamase B
beta lactamase C
beta lactamase D
beta-lactamase-like protein 2 (LACTB2)
beta-lactamase-like protein FLJ75971 (MBLAC2)
carbapenemase
extended spectrum beta lactamase (ESBL)
metallo-beta-lactamase domain-containing protein 1 (MBLAC1)
New Delhi metallo-beta-lactamase 1 (NDM-1)
penicillinase
General
amidohydrolase
bacterial protein
Properties
MOTIF: active site
MISC-INFO: EC-3.5.2.6
References
- Medical Knowledge Self Assessment Program (MKSAP) 17, 18.
American College of Physicians, Philadelphia 2015, 2018.
- Banach DB, Bearman G, Barnden M et al
Duration of Contact Precautions for Acute-Care Settings.
Infection Control & Hospital Epidemiology. Jan 11, 2018
PMID: 29321078
https://www.cambridge.org/core/journals/infection-control-and-hospital-epidemiology/article/duration-of-contact-precautions-for-acutecare-settings/94E38FDCE6E1823BD613ABE4E8CB5E56
- Woodworth KR, Walters MS, Weiner LM, et al.
Vital Signs: Containment of Novel Multidrug-Resistant Organisms
and Resistance Mechanisms - United States, 2006-2017.
MMWR Morb Mortal Wkly Rep. ePub: 3 April 2018.
https://www.cdc.gov/mmwr/volumes/67/wr/mm6713e1.htm