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beta cell
Function:
- secretes insulin & amylin
- proliferation of beta-cells is stimulated by betatrophin [2]
Structure:
- comprises 65-80% of islet cells
Note:
- adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation
General
islet cell
Properties
WITHIN: islets of Langerhans
References
- Journal Watch 24(13):107, 2004
Dor Y, Brown J, Martinez OI, Melton DA.
Adult pancreatic beta-cells are formed by self-duplication rather
than stem-cell differentiation.
Nature. 2004 May 6;429(6987):41-6.
PMID: 15129273
- Yi P, Park SJ, Melton DA
Betatrophin: A Hormone that Controls Pancreatic beta Cell
Proliferation.
Cell, 25 April 2013
PMID: 23623304
http://www.cell.com/abstract/S0092-8674(13)00449-2