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berdazimer (Zelsuvmi)
Indications:
- at home treatment of molluscum contagiosum (FDA-approved Jan 2024) [1]
* expected to be available in the U.S. by the 2nd half of 2024
Dosage:
- gel 10.3% [1]
Adverse effects:
- application site reactions [1]
Mechanism of action:
- gel contains a nitric oxide-releasing agent with antiviral activity
- precise mechanism of action unknown [1]
* effects not spectacular
- 30% of patients with complete or near complete response
- 10-15% improvement over control group [1]
General
antiviral topical
References
- Bankhead C
At-Home Treatment for Molluscum Contagiosum Wins FDA Approval.
Berdazimer gel led to 30% complete/near-complete clearance after 12 weeks in
randomized trials.
MedPage Today January 8, 2024
https://www.medpagetoday.com/dermatology/generaldermatology/108169