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benign migratory glossitis (geographic tongue)

Etiology: - may be observed in patients with psoriasis or atopic dermatitis - occurs in otherwise healthy persons - not linked to tobacco use or HIV1 infection Epidemiology: - about 2% of the population Pathology: - asymptomatic inflammation of the tongue with rapid loss & regrowth of filaform papillae Clinical manifestations: - generally asymptomatic - when symptomatic, causes pain while eating - does not cause taste disturbance [2] - appearance of denuded red patches migrating across the surface of the tongue - map-like erythematous patches with white hyperkeratotic rims on dorsal surface of tongue [7] - migratory: can change in appearance within minutes to hours * images [5] Special laboratory: - biopsy not required Differential diagnosis: - oral leukoplakia - patches or plaques of the oral mucosa, associated with tobacco or chronic trauma - oral hairy leukoplakia - adherent white plaques, associated with EBV, HIV1 infection - lichen planus - occurs in older persons, associated with chronic trauma or medications - lesions variable: reticular white plaques of the oral mucosa - erosions & ulcerations may be painful - oral candidiasis: - non-adherent white plaques or pseudomembranes [7] Management: - no therapy is required

General

glossitis

References

  1. Harrison's Principles of Internal Medicine, 14th ed. Fauci et al (eds), McGraw-Hill Inc. NY, 1998, pg 190
  2. Geriatric Review Syllabus, 7th edition Parada JT et al (eds) American Geriatrics Society, 2010
  3. Medical Knowledge Self Assessment Program (MKSAP) 17, American College of Physicians, Philadelphia 2015
  4. Kelsch RD, James WD Medscape: Geographic Tongue http://emedicine.medscape.com/article/1078465-overview
  5. DermNet NZ (images) Geographic tongue (benign migratory glossitis) http://www.dermnetnz.org/site-age-specific/geographic-tongue.html
  6. Shulman JD, Carpenter WM. Prevalence and risk factors associated with geographic tongue among US adults. Oral Dis. 2006 Jul;12(4):381-6. PMID: 16792723
  7. NEJM Knowledge+